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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2641ec7d6c95b076c8be2b70f1864415f027be2d7a71e084771997ac82886275' 
  AND token = 'tS4F0Xcw5M19XRyk5PHcBn0SWpyKD33lWMDUyOWE86U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}