SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6e78e71ad931171bdc27599ae5105907302715e12b564fbfc2755564b693fc' 
  AND token = 'GkeqaOvq9irZp3VJhY6rNJ25jSF4AKnZcQtwj1SJuCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}