SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f1521f61e8a81cfe6739f9393924a941c6e1282b841a9ec8be4bf877c0bfae' 
  AND token = 'M4OceqX9FnBgByiC+eajdLMvbDcaF0HhQNN0OBqfXyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}