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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f051f8b726fe360bbebe468b897373161b7d36fc29b9d304c70fc3cad6f4b1' 
  AND token = 'CUQrWnpq8vZ4SSczVqeQsHsF7Hukd18D+LpsZhHd0AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}