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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '082100d45aa745b6aeea62645bdb281054be5c91b0604626f6b0d2169eb2582e' 
  AND token = 'iwAIy415V6v+/RxrYoamOUCdtJPYb9SR3sLgE8x+9hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}