SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11af4068b8b3e65fe94a750fd065978792f5d6f4d435f73a8d496a49aa7fd263' 
  AND token = 'QOj4JPyZcG+Ac3HLwAE1rweX6TPsU5SFS8tVbW2lqag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}