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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e0f086cf23dde1a0b9dc73b1cb2a1cd3456d07477845bcda8b781e99f4e0c5' 
  AND token = 'pCuODM5oovhPthQ7c26nIoDj09xEfq5x8qOOXkGLB7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}