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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e18063de03b59fb73a01128d4f8b61a9ff25c02e9b867fb74703c58372af92' 
  AND token = 'G9cOmSBmjcPyHbI/RvOE6UWMIge3L/EHSs3ZOpnXBLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}