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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2a32250380ad81054a7f66c4b3e5e0181b189fd97e6272d6dd4365dfc3e24b' 
  AND token = 'Ax/qx5rMg2ZSTF3D9x2lJujlzWakx24s02zUukcBjwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}