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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d824b931427a7c399ecfa3f2951a94e10486a4add2fc4208dcb8a93f240fd2' 
  AND token = 'b5S7A/IbnPJrKUDsAwQhklF+kxVGOTaHdPdQj1AKaLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}