SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56aefe4274e2d6f41cf33c419640770de2b690c4f5b7727f2ea8f80e213384f8' 
  AND token = 't39XaToSXQ1MVW0pEVEFqXJxsFd/FqpN4pdRxIUQ/E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}