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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b12b2393eaf9109a99bb7a46a2497def6f60a88878564733c8554ed97c8293' 
  AND token = 'VRXJWV1hG6IM2XVnIz7JPn8O3SsZu8MIAzG5XZdrUII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}