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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5383edc599cff2103b7a9c95d977bb8a03966b6cda0b7cfcfb6d7e1e0b054342' 
  AND token = '2FfhzVnyMYdcA910BLJSkn0b/erdv53OveCDpopPHoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}