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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39447708dcd4c6fe8d955cda811b3a7ee234db039cf27110ae2c383d991813e6' 
  AND token = '4fkY/S1PPrEApa+tFfye/4XaA3/hmFrzUUxtquRVcLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}