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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c145f6301dfad65e8c3a4901ea04b5d8094778b1f0797e656cc8d5290410a29' 
  AND token = 'rlVxIvmncUZKlh/oDeCjSXxvt8pCj9yqIVzErX4bq38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}