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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21593896df76afc4a7ec9638067ab4b8483aab76eda9696e099c44aa78610bf' 
  AND token = 'yxWJs4Is7VbFN5OCbCXgzj7z8pgXEnWlpj/bjXpg2PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}