SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441bed9c91844d964d09e4653ad0b381ca612b4ed8a730f961f9da11f896667f' 
  AND token = 'takYvr7wlnhZRHD2Dc0dt2BRp9pQsl1eSIdh0PgpjgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}