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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65052b6ec269de59f23e88c6b39d0c80c0c07fac642a7d80be3116a6c40cb955' 
  AND token = 'zaqtRMeJ/bTTSfQxcZbYNUPoaNGew3g8Q20fiHL8IRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}