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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1456e9b82750d39521024f4a91eeaacc56f3b1b265441b822b36912a1c090df1' 
  AND token = 'AOZwCqbmi0K2CPqS3PSCR58G5C7iqPt67WO01aUto68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}