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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a5ec50be0c1b6d9bcd4966bc59394d230fcbffcc99f23a63873cb3390c1768' 
  AND token = 'GrFK80OTyrvA3TQrswq3Fj/XqGT8SZ8VhOorIbh2Ki0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}