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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db371e427bdf875c73a2800a0a915298e8628b8ed2690cf905cf46b99540acf' 
  AND token = '/wbvSvyhbkq7Sqn3BFcR4Rc1G0+Ef8+MU100Gs4hPn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}