SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c932c893b9541b3fe07520d60a5180a8e8c038299484dd1cbefb14907ae2e440' 
  AND token = 'ye6EnyIQUARJUBxKYB5PHAn2yZNtV5iyM1l0rCaUYKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}