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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b4ebf849da8210ca682d32f5cbb88c191ab59bd21c76e7ea7e4ddbfec50c66' 
  AND token = 'BoipWdHw3yiZKTO3LPHXaWXHi+wYd8L2uqgdlsoh9uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}