SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd0dfd73aedfec3ce270d4281e2e4c8f2682a2539d2d47f3a6300d42e7269ee' 
  AND token = 'l8+UR4ZTsE+KPeKSE2kpgqko9Yg+IHpycBjMQsKjSyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}