SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88efade192389bff97a6e62c0454109c11beba957a5adde2676e178a4a83ec0' 
  AND token = '9I/ZWQ0KgKtWza3TjlT8qZKnbK0IwfIbxtV58LWsBPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}