SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64325aac8184eeeff81cd60ec4f54b4fe63fe8a08c8183d9e2db231c1028dd3b' 
  AND token = 'jYKO7gOzYVIJUqVBDaG8WtrkxvEb2X8HTCf5vyK3A2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}