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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca17058266a703c6148939daad75ef7541fa4370d8bc7884e85a309712674d8a' 
  AND token = 'yJD5iihOOxcqCrid4XtPJkOiu779apw7NOcPjL27/sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}