SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5208021c6a9c27ca57084a6888813b8d9f1b7200b5cd0957625c7a87731a8382' 
  AND token = '8LB/zpqbvzrznRE4RmFHDZHoBLwwCmenLPU7BG7Ba6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}