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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e179c070cbe14808264d4a6516b7019c3044ff1a5852b61d163edf85f209105d' 
  AND token = 'kCZkHIZiXaVZpes3aclO29bZ48FQs2uyY8yU6N1vD9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}