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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1d1cff62833232a335e91cf02e2367d9acb13039042be742ce064e6624dc5f' 
  AND token = 'kO8aUi5Gfh63IumMHXZjv1b2/P19mj5Cb/DKpI8rPIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}