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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345141e77478b7e03ba1bbe6fa8f25b8afb49614c3fed1e30475955c849ed696' 
  AND token = 'LIIO+msjGiukV5Ui/GdPxIci/bYC3NtipV5nQiyWMt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}