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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6735155ee35e02dcd554749623fad22ae0343cb3011622c7aa803d6e65835c' 
  AND token = '75nFvPm/3et8eU2DIl7mLVF8HoIidYtRGDXBGm4p/I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}