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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c65e74cbb8eecbae002d5c5fdd6d054b3cef23324a71351022ab1bd064ad81' 
  AND token = '70ed8UXjDxO1oM6/6UGC0bFpHkXTZjCT/d86xNkGNS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}