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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c28a4a2d1cde07e03a6d0e1f6734895c13d3a652abf63f9354c02adb5b9b4a6' 
  AND token = 'khSc8+siUrxIcPi8iAHZAgd8mZiUHjQ42BKTZpXLtbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}