SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259c8a1ab5f4332f6fd64b8ca059ccdbf1f569f2d79e350440fc6abf7693fa42' 
  AND token = 'r0cyH+W2T+x85EYTL4JvG9B2AMPwdplLUStrpzBEKbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}