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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57a0af6ba5ea5cb9d8b50fe8b11a9fdfaeac3459f89df84843701a64340ca48' 
  AND token = '20uDzoJlI/TpU8leebnY/mi/qw4bC4f4gacKdZ+Z1Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}