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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38461b699b174442bf39ea597885ebc06dea1612a1aee95f6c6f5862eaf63b7f' 
  AND token = 'uxiiiwswI9PRH113EqYe0GUKCM6xHL/j+b3ObcV8WzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}