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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c66ccbfcdd4c9f6c20ce6da91c81e5569827d1066e06cec2cf7f331b9c976a8' 
  AND token = '0uB1+Gm/4xhTM5fOMrlwv/NXgy8ehhCwAhMDJwOIil0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}