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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10682af2060b3e6d0109b815b4f7c67cefc1e65007e79c18c6266257828b48c0' 
  AND token = 'ar4iS27TGOrY1jyUnZLxuRoZddH6xPqb+MfKbWxLTIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}