SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7851dbc11f440c514aef536c29bbc5bba38887ddf0f7e070c27119495d34f716' 
  AND token = 'vcwfKWmtBZ0mncz3RVQTDVX2gTct9Bi1S89A2CzAotg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}