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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9f34d03f3ba2daedc7e75c7a59b3363d88570ce671a90da9e9046a70de7580' 
  AND token = 'f2+XRGK5zVAqqd85cH6l9hWJUfkOttZUkLos6H4abdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}