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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583d3eff78211c79a2cbdfa303f9b4af05090d08701a086fe97e05504f5f8e4d' 
  AND token = 'cXuOn2VWZ8k9WY0oLKntwFLKzlN+mHYhU+pTCpeSjxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}