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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7ee34dae195b3c556ffecbc4d1de7c72152d20d63367568c70664b32e2e931' 
  AND token = 'HGY0FeVSX84eEiY+bqdFnuHgBMvh8jb0B0WISsmzdVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}