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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5054ffac60e47f0a13c903f7eaf810b9222b3a0f083a06f06a0f648ffc6b93a3' 
  AND token = 'PM4k6ke+gwjOMCKegw7LfKCSaSnNO0aQEkv1xkoYerY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}