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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7528bf90ceb6d77d3020d560b981c7af7624feb002ab8ccd7bdd8f5134e4c9' 
  AND token = 'wD1+AD7Rt23m9Oi1SS8wXkEPJTz2zgeht0lJbNYRU1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}