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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64fb4cf1308973ba1f6147c1b61ada21eb1fa824cf4a5bebad7639a4641fe86c' 
  AND token = '8wP5HbdzGDOHfakLKY7yFnbXIU4eBHxuKsDZ9pQxc4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}