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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c09c842b78b2b65dfaf25a56a8c00e5eb704c8b0ee933f41282ae87f07063a0' 
  AND token = 'B2h4TTSp5NWO3Nj2Y9rkDONxK7QtMDiSvo2ybmdb0ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}