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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f95fb5a9f0a319004cddccb00ec7bca550a29f98bb50ca30100cfa28179aeb2' 
  AND token = '734JwsPXbXInvlSMfe2ryS5pC7qhiKYeWVZoWjEPA1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}