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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d49dec051275ee091130eaeee12c864cd84143c2e701dd5c8af7e4aa11987cd' 
  AND token = '44y7ngjQPY+ZpoPWncqTnoLU5B9L/lvJhOJp0qSTbo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}