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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2ad78324537d3077f075055b00160215df19882c63e9c62c04b1f98d1327fc' 
  AND token = '0mVZZDgVxO5bNYAP84nlBedNPPgyTdq9I+JNuqDyCbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}